Sharing because I found this very interesting.

The Four Thieves Vinegar Collective has a DIY design for a home lab you can set up to reproduce expensive medication for dirt cheap, producing medication like that used to cure Hepatitis C, along with software they developed that can be used to create chemical compounds out of common household materials.

  • RangerJosie@lemmy.world
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    4 months ago

    Piracy is how you got Netflix.

    This is how we’ll change the pharmaceutical industry. They’ll overreact and Streisand Effect this and it’ll blow up. Become normalized. The open source tech will improve.

    This is a good thing. Period.

    • Mojave@lemmy.world
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      4 months ago

      Pirating movies and games can’t kill you

      Home brewing seizure medication can

      • RangerJosie@lemmy.world
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        4 months ago

        This is America dude. Human life costs $7.25 an hour here. We can’t even do anything to keep children safe from their number 1 killer here.

        Nobody cares. Those who do care are completely powerless to change anything.

        Yes. Mistakes will happen. People will die. People die every day right now. Many of them because they can’t afford life saving medicine. I’d happily take a risk on this before I’d saddle my family with $50,000 a month for medicine that you can get in Canada or Mexico for $50.

        • grue@lemmy.world
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          4 months ago

          We can’t even do anything to keep children safe from their number 1 killer here.

          By this the parent commenter means “car crashes,” by the way. Car dependent zoning is literally mass-murdering more children than school shooters ever did and we’re doing almost nothing to fix it.

  • captainlezbian@lemmy.world
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    4 months ago

    This is extremely dangerous and also something I feel must be considered a natural and obvious extension of a right I believe to be fundamental: bodily autonomy.

    Would I do this? Probably not, maybe for some medicines, that are easily made administrable from bulk chemicals but likely not. But behind all rights stands bodily autonomy. It is your flesh and not mine. If we don’t want people doing this themselves the lever we should use is easing access to expert made medicines. Desperate people do stupid things.

    Also this is cyberpunk as hell and aesthetically I’m so here for it

    • Fedizen@lemmy.world
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      4 months ago

      I think an off the shelf microlab that can reliably synthesize a particular medicine is something that’s commercially viable, which is probably a safe middle ground here and sort of what they’re proof of concepting.

      Rather than putting together a DIY lab like this, a pre-made kit that makes one medication would easily make a ton of meds available. Not just here but all around the world.

      I would say the next step would probably be to create a certification process for microlabs categorizing their safety and effectiveness

    • UnderpantsWeevil@lemmy.world
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      4 months ago

      This is extremely dangerous and also something I feel must be considered a natural and obvious extension of a right I believe to be fundamental: bodily autonomy.

      There is a significant distinction between the right to bodily autonomy and the right to distribute quack medicine. And that’s sort of the rub. As soon as you start marketing your product to third parties under false pretexts, we’re not longer talking about an individual’s right to self. And we get into an even more tangled web when we start talking about health care for children or the elderly, who lack the mental acuity to make informed choices.

      Also this is cyberpunk as hell and aesthetically I’m so here for it

      Everyone wants to get the military grade Sandevistan drive. Nobody thinks they’re going to succumb to cyberpsychosis.

  • 2pt_perversion@lemmy.world
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    4 months ago

    This is super cool and helpful as a resource but I really don’t think people without a chemistry background should be doing anything more than following precise instructions, hopefully with some form of verification test at the end. The idea to have people without a chemistry background use a forked version of askcos and just run with it is a little scary.

    The affordable Controlled Lab Reactor for diy is fantastic for helping people follow precise instructions to the letter just all of those instructions should be meticulously vetted by actual chemists and have some safeguard tests at the end where necessary. It seems the founder wants that vision too at the end of the conference just there’s not enough of a community yet to support it.

    • TranscendentalEmpire@lemm.ee
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      4 months ago

      Yeah… This is a bit sketchy. Pharmaceuticals aren’t just something that an amateur can make by following step by step instructions. Even something as simple as baking a cake requires some basic experience to know when things are going right or wrong.

      Even maintaining the calibration on a CLR requires some background experience, let alone building and programming one all on your own. With your actual reactor being as small as a mason jar, it means the margin for error is going to be small as well.

      This is neat for people with a background in chemistry, but I don’t really see it as anything but dangerous for the general public. They also are fudging their math a bit to make things seem a lot cheaper. Reagents can be really cheap at bulk prices, but you have to spend the time looking for them, and they aren’t equating the cost of a trained chemist making these medications.

  • BartyDeCanter@lemmy.sdf.org
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    4 months ago

    This seems both awesome and dangerous. The two analogies that come to mind are home canning and home brewing. They’re both generally safe and easy. But every so often someone gives their family botulism.

  • MerchantsOfMisery@lemmy.ml
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    4 months ago

    Four Thieves are legit. Controversial but they’re confronting a lot of uncomfortable truths that need to be addressed .

  • krelvar@lemmy.world
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    4 months ago

    When a person has nothing left to lose they will take chances that otherwise they wouldn’t. If we weren’t living in a corporatocracy, perhaps there’d be no demand for this sort of thing, but we do and there is.

  • flicker@lemmy.world
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    4 months ago

    I believe every American knows someone whose life is made substantially worse because of a lack of access to healthcare.

    I want to set this up and learn to use it. I want to keep it and maintain it and wait. Because I’ll inevitably hear from someone that they can’t afford their life-saving medication.

    • flicker@lemmy.world
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      4 months ago

      Oh, also I have an exceedingly rare hereditary disease, so it feels like a certainty I’ll need it for myself someday.

    • ccdfa@lemm.ee
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      4 months ago

      I know someone whose life is made substantially worse because they have a lack of access to healthcare. They live in Europe and can’t get access to the specialized medicine that they need in the timeframe that they need it in. I’m not saying that socialized medicine is bad—I’m actually all for it—but it needs to be implemented well for it to actually work. This is just my anecdotal evidence to say that just because everyone has access doesn’t automatically mean it’s adequate access.

      • flicker@lemmy.world
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        4 months ago

        I can’t really comment on the European experience though, so I said American, which I am, and which I am qualified to talk about.

  • Sterile_Technique@lemmy.world
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    4 months ago

    …well, this is a good way to shine the spotlight on a massive problem. I’d be pretty hesitant to take DIY meds unless it was life-critical and my only option (which… lots of don’t have that option, and just die after hitting the health paygate…). The value here is its potential to slap some sense into the US and get our broken-as-fuck healthcare system caught up with the rest of the world so people don’t need moonshine insulin or w/e in the first place.

    That this conversation is even taking place is testament to how horrible our current system is.

  • LordCrom@lemmy.world
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    4 months ago

    Idk. Medicine is one of those skills where I prefer someone that has studied for 7 years vs me who watches a 15 min how to video and read webmd

    • krashmo@lemmy.world
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      4 months ago

      Obviously the people who would benefit most from this technology would prefer a doctor and pharmacy to be involved as well. The point is that personal preference doesn’t really mean much when the preferred option is inaccessible and the alternative is death or a dramatically reduced quality of life. You do the best with what you have.

    • ArchRecord@lemm.eeOP
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      4 months ago

      Well that’s the coolest part about this, everything is based on the existing research.

      The drugs they’re making are the exact same chemical compounds formulated by the drug companies, and contrary to popular belief, the compounds can actually be relatively simple, it’s the process of finding which compound that takes the most money from R&D.

      So if you have 2-3 very standard chemicals, with well known reactions and outcomes, and you have the exact blueprint of what the final result should look like, and you can chemically test it afterward to see if it combined as expected, then anyone who has enough reason to use this instead of traditional means (i.e. being priced out of lifesaving medication completely) can be reasonably confident it will work.